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1 article(s) from Eckert, Heiner

Efficiency Eff_syn of complex syntheses as multicomponent reactions, its algorithm and calculations based on concrete criteria

Heiner Eckert

Beilstein J. Org. Chem. 2019, 15, 1425–1433, doi:10.3762/bjoc.15.142

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Graphical Abstract

Scheme 1: Case study of a complex synthesis, parallel reactions. 10 possible synthesis STMs in green, other 1...

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Scheme 2: Ordered reactions of the above complex synthesis to a main reaction set and connected parallel reac...

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Scheme 3: Section A–J case study of Scheme 2 with operations of y_oa calculation.

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Scheme 4: Sequential synthesis and fragment linking of a decapeptide with comparison of results in Equations ...

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Scheme 5: U-4CR with 17 precursors in the total synthesis of Et-743 (1) [14].

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Scheme 6: Synthesis of 4 as key step of (+)-20S-camptothecin (3) total synthesis.

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Published 27 Jun 2019

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Efficiency Effsyn of complex syntheses as multicomponent reactions, its algorithm and calculations based on concrete criteria

Efficiency Eff_syn of complex syntheses as multicomponent reactions, its algorithm and calculations based on concrete criteria